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Reported variable groups in synthetic methodology papers in the first issues in 2016 of Angew. Chem. Int. Ed. and J. Am. Chem. Soc. (see the Supporting Information). A) Variation in terms of aryl and hetaryl substitution. B) The proportion of functionalizable (het)aryl versus unfunctionalizable (het)aryl groups incorporated. C) Variation of phenyl substitution. Charts are scaled according to the number of examples in the data set [504 examples for (A) and (B), 321 examples for (C)].
