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. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: Neuropsychol Rev. 2012 Apr 13;22(2):195–209. doi: 10.1007/s11065-012-9194-1

Fig. 4.

Fig. 4

Confocal microscopy image (with orthogonal views) of Bromodeoxyuridine+cells (BrdU+; green) in a PTD brain co-localized with the cells immune positive for the neuronal marker NeuN (Neuronal Nuclei; red) in the subgranular zone (SGZ) of the dentate gyrus. PTD treatment produces a significant deficit in spontaneous alternation (a), chronically decreases hippocampal brain-derived neurotrophic factor (BNDF; b) and reduces hippocampal neurogenesis (c). Co-localized labels of BrdU/NeuN appear yellow and can be confirmed in all three projections (d)