Table 1.

Markers for memory T cell subsets^*

Memory T cell subset		Mouse phenotype	Human phenotype
Conventional T cells	Central memory	CCR7hi, CD44hi, CD127hi, L-selectinhi and KLRG1low	CD44hi, CD45ROhi, CD45RAlow, CD127hi and express high levels of IL-2 and intermediate levels of IFNγ and TNF
	Effector memory	CCR7low, CD44hi, CD127hi, L-selectinlow and KLRG1hi	CD44hi, CD45ROhi, CD45RAlow, CD127hi, L-selectinlow, express high levels of IFNγ and TNF and express low levels of IL-2
	Tissue-resident memory	CCR7low, CD69hi, CD103hi and KLRG1low	CD45ROhi, CD45RAlow, CD69hi; and CD103hi and CD103low subsets
	Stem cell memory	CD44low, L-selectinhi, CD95hi, CD122hi, SCA1hi, BCL-2hi and CD127hi	CD27hi, CD28hi, CD45ROlow, CD45RAhi, CD95hi, CD122hi, CD127hi, L-selectinhi, CCR7hi and express low levels of IFNγ and intermediate levels of IL-2
Memory regulatory T cells‡		CD25hi, CD27hi, CD44hi, FOXP3hi, L-selectinlow, CTLA4hi and CD127hi§	CD25hi, CD27hi, CD44hi, CD45ROhi, CD45RAlow, CCR7low, FOXP3hi, L-selectinlow, CTLA4hi, CD127low, ICOShi, BCL-2hi, Ki67low and HLA-DR expression not defined

BCL-2, B cell lymphoma 2; CCR7, CC-chemokine receptor 7; CTLA4, cytotoxic T lymphocyte antigen 4; FOXP3, forkhead box P3; ICOS, inducible T cell co-stimulator; IFNγ, interferon-γ; IL-2, interleukin-2; KLRG1, killer cell lectin-like receptor subfamily G member 1; SCA1, stem cell antigen 1; TNF, tumour necrosis factor.

^*Table compiled fromREFS 1,7,11–16,19,29,30,40,64,65,74,103–106.

^‡It is currently unknown whether memory regulatory T cell subsets exist in mice or humans.

^§Shown only in mouse skin.