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. 2016 Sep 4;56(8):1317–1332. doi: 10.1111/head.12896

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© 2016 The Authors Headache published by Wiley Periodicals, Inc. on behalf of American Headache Society

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Response rate^a (ITT Population). CH, cluster headache; CI, confidence interval; ITT, intent‐to‐treat; nVNS, non‐invasive vagus nerve stimulation. ^a Response rate was defined as the proportion of subjects who achieved a pain intensity score of 0 or 1 on a 5‐point scale (0, no pain; 4, very severe pain) at 15 minutes and had no rescue medication use through 60 minutes after treatment initiation for the first CH attack in the double‐blind phase. P values are from Fisher's exact test (if ≥1 cell had an expected frequency of ≤5) or the chi‐square test. ^bPrimary end point. ^cPrespecified subanalysis.