Phylogenetic analyses of Thiocapsa KS1 NXR and related enzymes of the dimethyl sulfoxide reductase type II family. Bayesian inference tree of the large (NxrA) subunit. Names of validated enzymes are indicated (Clr, chlorate reductase; Ddh, dimethylsulfide dehydrogenase; Ebd, ethylbenzene dehydrogenase; NAR, nitrate reductase; Pcr, perchlorate reductase; Ser, selenatereductase). The arrow indicates the outgroup; the scale bar represents 10% estimated sequence divergence. Enzyme complexes with the active center located on the cytoplasmic side of the membrane are indicated in blue, complexes oriented toward the periplasm in red. Names of organisms containing a NXR are shown in green. Note the three independent origins of NXR.