Table 5.
Odds ratios (OR), 95% confidence intervals (95% CI), positive (PPV) and negative predictive values (NPV) for sum scores of 5 selected genotypes
| Full or partial response (N = 179) | Nonresponse (N = 60) | OR | 95% CI | PPV | NPV | |
|---|---|---|---|---|---|---|
| Number of variants | ||||||
| None (N = 26) | 25 | 1 | 1 (ref) | 0.96 | 0.04 | |
| 1 (N = 82) | 58 | 17 | 7.33 | 0.92–58.10 | 0.77 | 0.23 |
| 2 (N = 68) | 45 | 21 | 11.67a | 1.48–91.98 | 0.68 | 0.32 |
| 3 (N = 45) | 33 | 10 | 7.58 | 0.91–63.13 | 0.77 | 0.23 |
| 4 (N = 23) | 15 | 8 | 13.33a | 1.51–117.38 | 0.65 | 0.35 |
| 5 (N = 6) | 3 | 3 | 25.00a | 1.93–323.55 | 0.50 | 0.50 |
Data from Bank et al.25
Genotypes: TLR2 rs4696480TT, TLR2 rs11938228AC, IL6 rs10499563TT, IL12B rs3212227AC, and IL12B rs3212217CG.
a
P < 0.05.