Table 2.
Comparison of laboratory findings among the groups
| Laboratory findings | Group 1 (n=22) | Group 2 (n=36) | Group 3 (n=29) | F or χ2 | P-values |
|---|---|---|---|---|---|
| WBC (×109/L) | 7.9±2.2 | 8.7±2.0 | 10.3±2.8*,** | 7.141 | 0.001 |
| Neutrophils% | 58.8±13.2 | 56.1±11.3 | 57.9±11.8 | 0.373 | 0.690 |
| Lymphocyte% | 29.3±14.0 | 33.1±12.6 | 38.8±11.3 | 1.109 | 0.270 |
| Hemoglobin (g/L) | 126.4±14.5 | 126.0±9.5 | 124.6±10.8 | 1.953 | 0.148 |
| Platelet (×109/L) | 246.7±92.5 | 251.3±71.3 | 255.0±80.3 | 0.427 | 0.654 |
| CRP (mg/L) | 7.6±4.6 | 11.8±7.0* | 16.7±8.3*,** | 10.957 | 0.000 |
| ESR (mm/h) | 15.4±5.0 | 17.3±6.5 | 19.4±8.5 | 2.129 | 0.125 |
| PCT (ng/mL) | 0.15 (0.08–0.28) | 0.34 (0.10–0.54) | 0.25 (0.08–0.90) | 4.558 | 0.102 |
| LDH (IU/L) | 304.5±58.8 | 355.6±68.1* | 360.1±83.7*,** | 12.077 | 0.000 |
| IL-2 (pg/mL) | 12.7±3.8 | 15.1±4.7 | 14.3±5.2 | 1.881 | 0.155 |
| IL-4 (pg/mL) | 6.0±3.0 | 12.1±9.9* | 17.0±9.8* | 9.462 | 0.000 |
| IL-6 (pg/mL) | 43.7±24.1 | 70.0±47.7 | 95.4±49.3*,** | 8.862 | 0.000 |
| IL-10 (pg/mL) | 16.9±6.9 | 26.3±10.4* | 28.5±12.6* | 8.359 | 0.000 |
| IFN-γ (pg/mL) | 24.8±8.8 | 37.0±15.4* | 42.8±12.4* | 12.206 | 0.000 |
| TNF-α (pg/mL) | 32.2±6.3 | 46.6±15.1* | 74.1±20.5*,** | 48.553 | 0.000 |
Notes: Data presented as mean ± standard deviation, or medians and interquartile ranges (25th–75th percentiles).
*
P<0.05 versus group 1.
**
P<0.05 versus group 2.
Abbreviations: WBC, white blood cell; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; PCT, procalcitonin; LDH, lactate dehydrogenase; IL-2, interleukin-2; IL-4, interleukin-4; IL-6, interleukin-6; IL-10, interleukin-10; IFN-γ, interferon-γ; TNF-α, tumor necrosis factor-α.