. 2016 Nov 11;12:1667–1675. doi: 10.2147/TCRM.S115014

Table 2.

Incidence rates for special interest events

Adverse event of special interest	Response	n (%)	Incidence rate^a
Clinically significant AEs	Yes	216 (23)	0.098
Clinically significant AEs	No/not recorded	725 (77)	0.098
Medical attention required due to fall-related injury	Yes	61 (6)	0.028
Medical attention required due to fall-related injury	No/not recorded	880 (94)	0.028
Other significant psychiatric or psychotic events	Yes	55 (6)	0.025
Other significant psychiatric or psychotic events	No/not recorded	886 (94)	0.025
Suicidal thoughts or attempted suicide	Yes	15 (2)	0.007
Suicidal thoughts or attempted suicide	No/not recorded	926 (98)	0.007
Change in driving ability	Improved	63 (7)	0.028
	Deteriorated	19 (2)	0.009
	Both improved and deteriorated^b	2 (0.2)	0.001
	No change	303 (32)
	Not appropriate	514 (55)
	Not recorded	40 (4)

Notes:

Per year of THC:CBD exposure, calculated by dividing the number of patients reporting the AE of special interest by the total patient-years of THC:CBD exposure in the Registry (2,213.98 years).

Improvement and deterioration reported at different DCPs.

Abbreviations: AE, adverse event; CBD, cannabidiol; DCP, data collection period; THC, Δ⁹-tetrahydrocannabinol.