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. 2016 Nov 11;11:6003–6022. doi: 10.2147/IJN.S118727

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© 2016 Han et al. This work is published and licensed by Dove Medical Press Limited

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(A) CAC measurement using pyrene as fluorescent probe: plots of the intensity ratio (I₃/I₁) from pyrene emission spectra versus the logarithm concentration of SAHA-S-S-VE/TPGS NPs. (B and C) Stability of SAHA-S-S-VE/TPGS NPs in human plasma. SAHA-S-S-VE/TPGS NPs were incubated in human plasma for 0, 4, 8, 12, and 24 h.

Abbreviations: CAC, critical aggregation concentration; TPGS, d-a-tocopheryl polyethylene glycol succinate; NP, nanoparticle; PDI, polydispersity index; h, hours.