Table 2.
Variable (median, range) | Control (N=55) |
22q11.2 DS (N=36) |
p-value |
---|---|---|---|
Pre-operative values | |||
| |||
PTT, seconds | 33.7 (24.1–119.1) a | 35.2 (24.0–200.0) b | 0.74 |
PT, seconds | 13.1 (11.1–18.6) a | 13.3 (11.3–17.2) b | 0.48 |
Fibrinogen, mg/dL | 266 (115–503) a | 284 (125–452) b | 0.17 |
Hematocrit, % | 41.7 (28.0–57.3) | 39.8 (30.2–52.1) | 0.10 |
Mean platelet volume, fL | 7.5 (5.7–11.1) | 10.4 (6.4–15.2) | <0.0001 |
Platelet count, × 103/μL | 305 (95–688) | 235 (54–506) | 0.0006 |
| |||
Post-operative values – Day 1 | |||
| |||
Hematocrit, % | 40.4 (25.6–56.2) | 41.3 (27.3–54.1) | 0.95 |
Platelet count, × 103/μL | 183 (73–405) * | 135 (69–506) * | 0.001 |
PTT = partial thromboplastin time; PT = prothrombin time
n=53;
n=35;
Denotes significant difference (p<0.0001) relative to pre-operative platelet count
Bold font depicts p-value<0.05