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. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: Nat Immunol. 2010 Mar 14;11(4):295–302. doi: 10.1038/ni.1855

Table 1.

B. burgdorferi clearance from mouse organs

B. burgdorferi flaB (103 copies per mg tissue)
Bladder Heart Joint Liver Spleen
WT 16.8 ± 0.2 20.4 ± 1.7 2.3 ± 0.3 23.0 ± 9.4 10.5 ± 0.8
+CLL, WT 48.0 ± 0.2*** 31.6 ± 1.5** 12.9 ± 0.8** 52.2 ± 5.7 25.9 ± 3.6*
−Spl, WT 12.8 ± 1.2 17.8 ± 1.2 2.1 ± 0.4 36.8 ± 1.2
Cd1d−/− 23.7 ± 1.5* 10.4 ± 1.9* 59.4 ± 0.6*** 36.2 ± 1.1 10.9 ± 0.6

B. burgdorferi clearance in untreated, CLL-treated or splenectomized wild-type mice and in Cd1d−/− mice at 3 d after B. burgdorferi infection, assessed by quantitative PCR analysis of B. burgdorferi flaB (pooled DNA samples).

*

P < 0.05,

**

P < 0.01 and

***

P < 0.001, versus wild-type (Bonferroni’s mutiple-comparison test).

Data represent one experiment with three to five mice, depending on experimental group (mean and s.e.m. of two independent measurements).