Table 2. Patient characteristics: antiplatelet therapy and coronary artery disease severity.
| All | Low PFS | No P2Y12 inhibitor | High PFS | p Value low-medium-high | Low PFS | P2Y12 inhibitor | High PFS | p Value low-medium-high | p Value no P2Y12 vs. P2Y12 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Medium PFS | Medium PFS | |||||||||
| N | 195 | 9 | 43 | 63 | 31 | 36 | 13 | |||
| Medical therapy | ||||||||||
| Aspirin (n, %) | 151 (77.4) | 6 (66.7) | 33 (76.7) | 39 (61.9) | 0.275 | 28 (90.3) | 32 (88.9) | 13 (100.0) | 0.465 | < 0.001 |
| Clopidogrel (n, %) | 66 (33.8) | – | – | – | 23 (74.2) | 33 (91.7) | 10 (76.9) | 0.145 | < 0.001 | |
| Prasugrel (n, %) | 3 (1.5) | – | – | – | 2 (6.5) | 1 (2.8) | 0 (0.0) | 0.541 | 0.142 | |
| Ticagrelor (n, %) | 10 (5.1) | – | – | – | 7 (22.6) | 2 (5.6) | 1 (7.7) | 0.093 | < 0.001 | |
| Vitamin K antagonists (n, %) | 28 | 1 (11.1) | 6 (14.0) | 8 (12.7) | 0.960 | (9.7) | 9 (25.0) | 1 (7.7) | 0.157 | 0.870 |
| Indication for angiography | ||||||||||
| Stable CAD (n, %) | 145 (74.4) | 5 (62.5) | 37 (88.1) | 55 (96.5) | 0.006 | 16 (53.3) | 22 (64.7) | 10 (76.9) | 0.317 | <0.001 |
| Unstable CAD (n, %) | 39 (20.0) | 3 (37.5) | 5 (11.9) | 2 (3.5) | 14 (46.7) | 12 (35.3) | 3 (23.1) | |||
| Angiographic CAD severity | ||||||||||
| Nonsignificant (n, %) | 54 (27.7) | 3 (33.3) | 12 (27.9) | 30 (47.6) | 0.116 | 3 (9.7) | 4 (11.1) | 2 (15.4) | 0.861 | <0.001 |
| Significant (n, %) | 141 (72.3) | 6 (66.7) | 31 (72.1) | 33 (52.4) | 28 (90.3) | 32 (88.9) | 11 (84.6) | |||
| SYNTAX score | 13.2 | 10.0 | 8.0 | 0.304 | 13.5 | 7.0 | 0.032 | 0.261 | ||
| (median, IQR) | 10.0 (5.0,16.0) |
(11.9, 19.1) | (5.0, 14.0) | (5.0, 13.0) | 8.5 (5.1, 13.1) |
(9.6, 20.0) | (5.0, 11.5) | |||
| Treatment CAD | ||||||||||
| Conservative (n, %) | 74 (37.9) | 3 (33.3) | 18 (42.9) | 38 (61.3) | 0.205 | 6 (20.0) | 6 (16.7) | 3 (23.1) | 0.893 | <0.001 |
| PCI (n, %) | 103 (52.8) | 4 (44.4) | 20 (47.6) | 19 (30.6) | 22 (73.3) | 28 (77.8) | 10 (76.9) | |||
| CABG (n, %) | 15 (7.7) | 2 (22.2) | 4 (9.5) | 5 (8.1) | 2 (6.7) | 2 (5.6) | 0 (0.0) | |||
Abbreviations: CAD, coronary artery disease; CABG, coronary artery bypass graft; IQR, interquartile range; PCI, percutaneous coronary intervention; PFS, platelet function score.
Note: Data are shown as percentage, or median with IQR. Significant values (p < 0.05) are given in bold.