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. 2016 Oct 1;16(4):327–338. doi: 10.1007/s40268-016-0144-x

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Average cost-effectiveness ratio of microneedle (MN) patches compared with subcutaneous (SC) injection at different levels of compliance rate of MN patches. Average cost-effectiveness ratio = (average cost-effectiveness of SC injection technology)/(average cost-effectiveness of MN patch technology). In cost-effectiveness ratios calculations, effectiveness of vaccines was set at 85 % and the vaccine coverage level was set at 95 % for both vaccination technologies