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. 2016 Nov 18;10:529. doi: 10.3389/fnins.2016.00529

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Copyright © 2016 Cho, Smith and Delgado.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enhanced VLPFC connectivity with PCC and precentral gyrus during free choice compared to forced choice. Psychophysical interaction (PPI) analysis was implemented to test whether free choice elicited greater VLPFC connectivity with other brain regions as a function of individuals' reward sensitivity scores. The seed region, (VLPFC; image on the left), exhibited enhanced connectivity with PCC and precentral gyrus (image on the right), contingent upon reward sensitivity (image in the middle). PCC is a region that has been previously associated with cognitive control, along with VLPFC. This connectivity relationship was enhanced for individuals who reported greater valuation for rewards.