Table 2.

Key topics identified in the literature search and pertinent questions for follow-up

Key topic	Questions
1. Definitions	What is the proper definition of persistent/residual disease? What is the proper definition of recurrent disease?
2. Follow-up intervals	What is the first time point for imaging during follow-up? What is the ideal follow-up interval? What is the ideal length of follow-up?
3. Imaging modality	Which one is the imaging modality of choice? Which alternative imaging modality in case of CKD? What are the proper CT/MRI protocols to be used? Is radiation exposure an issue during the follow-up?
4. Follow-up for metastasis	Which imaging test is recommended in the follow-up for metastasis? Which is the recommended follow-up schedule for metastasis?
5. Role of biopsy in follow-up	What is the role of biopsy in case of suspicion of residual/persistence or recurrence?
6. Risk stratification-adapted follow-up	Should follow-up be adapted to risk stratification? Which risk factors should be used?