Table 1.
Demographics and clinical characteristics of recruited patients
| Total | <3 years | 3 to <18 years | |
|---|---|---|---|
| No. of patients | 101 | 27 | 74 |
| Age (years) | |||
| Median | 5.3 | 1.6 | 7.3 |
| Range | 0.2–17.7 | 0.2–2.9 | 3.0–17.7 |
| Height (cm) | |||
| Median | 111.5 | 84 | 129 |
| Range | 52–194 | 52–97 | 89–194 |
| Weight (kg) | |||
| Median | 19.2 | 11.1 | 26 |
| Range | 3.6–88.1 | 3.6–14.7 | 111.5–88.1 |
| Doxorubicin dose (mg/m 2 ) | |||
| Median | 28.7 | 29.1 | 28.6 |
| Range | 10.4–57.7 | 10.4–57.7 | 18.2–56.8 |
| Doxorubicin infusion duration (h) | |||
| Median | 3.88 | 3.95 | 3.88 |
| Range | 0.25–24.02 | 0.25–24 | 0.28–24.02 |
| Gender | |||
| Male | 50 | 11 | 39 |
| Female | 51 | 16 | 35 |
| Tumor type | |||
| Wilms tumor | 12 | 3 | 9 |
| Neuroblastoma | 9 | 4 | 5 |
| Ewing sarcoma | 27 | 1 | 26 |
| Soft tissue sarcoma | 16 | 5 | 11 |
| ALL | 30 | 7 | 23 |
| Other | 7 | 7 | 0 |
| Country | |||
| France | 24 | 6 | 18 |
| Germany | 29 | 6 | 23 |
| Italy | 27 | 10 | 17 |
| UK | 21 | 6 | 15 |