Fig. 4.

Effects of the BuOH-soluble fraction of Fujian Chaka, chakasaponin II (12), desacyl-floratheasaponin B, and 5-HT on food intake in normal mice and/or capsaicin-pretreated mice. Male ddY mice were fed a standard laboratory chow MF (Oriental Yeast Co., Ltd.) for 8 days. The test sample was given orally once a day. b, c These doses are equivalent to approximately 0.2–0.4 mg/kg serotonin. Each value represents the mean of 5 or 6 mice. Significant differences where **p < 0.01 and ^† p < 0.05 or ^†† p < 0.01 were compared with controls and capsaicin-treated group, respectively.

Data were taken from reference [14]