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. 2016 Jun;16(2):145–151.

Figure 1.

Figure 1

Analysis of the mRNA expression of TRPV1, and ASIC1, 2 and 3 in the femur bone tissue. An array of nociceptors (TRPV1, ASIC2 and 3, and P2X2 and 3) were expressed in bone tissue of OVX mice (A). The expression levels of ASIC1 (*p<0.01) and P2X2 (**p<0.05) were significantly increased in OVX mice (n=6) compared with those in sham mice (n=6). The expressions levels of TRPV1, ASIC2 and 3, and P2X3 were increased in OVX mice although there were no significant differences between the two groups (B). Expression levels were shown as the ratio of the gene of interest to the control gene (GAPDH). The RT-PCR picture (A) demonstrated a representative data and the error bars (B) meant variation of the samples from different mice in independent femurs.