Table 2.
Demographic Data of the Derivation Cohort
| IPF | a-ILD | Healthy Control Subjects | P Value* | P Value† | |
|---|---|---|---|---|---|
| N | 86 | 41 | 127 | ||
| Age, yr (mean ± SD) | 63 ± 8.8 | 58 ± 14.0 | 64 ± 10.4 | 0.02 | 0.6 |
| Male, n (%) | 62 (72) | 22 (54) | 57 (45) | 0.04 | <0.0001 |
| Ever smoked, n (%) | 60 (72.3) | 21 (56.8) | 74 (65.5) | 0.09 | 0.3 |
| FVC, % predicted (mean ± SD) | 62 ± 16 | 65 ± 22 | 97 ± 15 | 0.45 | <0.0001 |
| FEV1, % predicted (mean ± SD) | 68 ± 16 | 67 ± 21 | 97 ± 15 | 0.81 | <0.0001 |
| DlCO, % predicted (mean ± SD) | 44 ± 18 | 56 ± 20 | 86 ± 18 | 0.002 | <0.0001 |
Definition of abbreviations: a-ILD = alternative interstitial lung disease; DlCO = diffusing capacity of the lung for carbon monoxide; IPF = idiopathic pulmonary fibrosis.
*
P value represents the comparison between the IPF and a-ILD cohort.
†
P value represents the comparison between the IPF and control cohort.