Table 1.
Vonoprazan (n = 14) | Lansoprazole (n = 12) | P value | |
Backgrounds | |||
Age (yr) | 71.9 ± 7.9 | 74.8 ± 8.3 | 0.371 |
Sex (M/F) | 12/2 | 10/2 | 0.867 |
Anticoagulants | 1 (7.1) | 1 (8.3) | 0.910 |
Antiplatelet agents | 3 (21.4) | 3 (21.4) | 0.829 |
Steroids | 1 (7.1) | 0 (0) | 0.345 |
Helicobacter pylori infection | 4 (28.6) | 5 (0.417) | 0.484 |
Atrophic gastritis | |||
Closed type | 3 (21.4) | 0 (0) | 0.088 |
Open type | 11 (78.6) | 12 (100.0) | |
Location | |||
Upper | 1 | 0 | 0.618 |
Middle | 5 | 4 | |
Lower | 8 | 8 | |
ESD results | |||
En bloc resection | 14 (100.0) | 12 (100.0) | |
Procedure time (min) | 88 (36-246) | 51.5 (12-202) | 0.123 |
Submucosal fibrosis | 3 (25.0) | 1 (8.3) | 0.356 |
Histopathology | |||
Tub1 | 12 | 10 | 0.504 |
Tub1 + tub2 | 1 | 2 | |
Tub1 + tub2 + por2 | 1 | 0 |
Data were expressed as number (%), mean ± SD, or median (range). A P value less than 0.05 was considered significant. M: Male; F: Female; ESD: Endoscopic submucosal dissection.