Table 3.

Characterization of LV hemodynamics in vivo in prediabetes by means of pressure-volume analysis

	CON	PRED
MAP, mmHg	110.100 ± 7.300	113.600 ± 6.100
LVESP, mmHg	116.600 ± 5.600	120.000 ± 6.800
LVEDP, mmHg	4.400 ± 0.400	4.000 ± 0.200
LVEDV, μl	292.800 ± 14.500	280.200 ± 9.600
LVESV, μl	130.700 ± 6.900	127.500 ± 4.500
SV, μl	162.100 ± 9.100	152.800 ± 7.700
CO, ml/min	59.500 ± 3.200	56.600 ± 2.300
EF, %	55.300 ± 1.300	54.400 ± 1.300
SW, mmHg·ml	14.500 ± 0.500	13.600 ± 0.600
dP/dtmax, mmHg/s	7226.000 ± 487.000	7387.000 ± 401.000
dP/dtmin, mmHg/s	−8198.000 ± 680.000	−8551.000 ± 545.000
τ (Glantz), ms	12.600 ± 0.300	12.100 ± 0.400
TPR, (mmHg·min)/ml	1.900 ± 0.190	2.000 ± 0.120
Slope of ESPVR, mmHg/μl	2.680 ± 0.120	2.710 ± 0.060
Slope of EDPVR, mmHg/μl	0.026 ± 0.001	0.037 ± 0.004*
PRSW, mmHg	100.500 ± 5.200	98.900 ± 4.100
Slope of dP/dtmax-EDV, (mmHg/s)/μl	34.300 ± 2.300	35.200 ± 2.200
Maximal power, mW	91.800 ± 8.200	98.200 ± 12.500

Data are means ± SE for 10 rat per group (

^*P < 0.05).

MAP, mean arterial pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic pressure; LVESV, LV end-systolic volume; LVEDV, LV end-diastolic volume; SV, stroke volume; CO, cardiac output; EF, ejection fraction; SW, stroke work; dP/dtmax, maximal slope of LV systolic pressure increment; dP/dtmin, maximal slope of LV diastolic pressure decrement; τ, time constant of LV pressure decay; TPR, total peripheral resistance; ESPVR, end-systolic pressure-volume relationship; EDPVR, end-diastolic pressure-volume relationship; PRSW, preload recruitable SW; dP/dtmax-EDV, slope of the dP/dtmax-end-diastolic volume relationship.