Table 1.
Acute liver failure (n = 16) | Acute hepatitis (n = 46) | Healthy control (n = 22) | |
Age (yr) | |||
Mean ± SD | 24.88 ± 21.52 | 21.21 ± 10.32 | 24.64 ± 8.79 |
25%, 75% | 9.25, 49 | 9.1, 29.75 | 15.2, 47 |
Gender | |||
Male | 6 (37.50) | 25 (54.34) | 9 (40.9) |
Diagnosis | |||
Hepatitis A | 11 (68.75) | 38 (82.60) | 0 |
Drug toxicity | 2 (12.50) | 2 (4.34) | 0 |
Indeterminate | 3 (18.75) | 6 (13.04) | 0 |
Liver enzymes | |||
AST (UI/L) | 1095.5 ± 1460 | 344.5 ± 444.9 | 21.68 ± 4.87 |
ALT (UI/L) | 806.12 ± 639.11 | 517.90 ± 884.30 | 14.36 ± 4.50 |
Total bilirubin (mg/dL) | 21.47 ± 10.48 | 10.01 ± 6.88 | 0.85 ± 0.09 |
Coma grade | |||
0-I | 3 (18.75) | 0 | 0 |
II-IV | 13 (81.25) | 0 | 0 |
Coagulopathy | |||
INR (mean ± SD) | 4.88 ± 0.99 | 1.16 ± 0.04 | 0.98 ± 0.06 |
Outcome | |||
Survived | 6 (46.15) | 46 (100.00) | 22 (100) |
Died | 10 (53.84) | 0 | 0 |
INR: International normalized ratio; SD: Standard deviation; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.