Table 3.
Potential clinical and inflammatory parameters as indicators of acute liver failure syndrome and death
| Cut-off | Adjusted OR | 95%CI | P value | |
| Plasma variables1 | ||||
| IL-6 (pg/mL) | > 197.6 | 1.36 | 0.04-40.27 | 0.856 |
| IL-10 (pg/mL) | > 55.77 | 18.86 | 1.38-257.94 | 0.028 |
| TNFα (pg/mL) | > 122.6 | 4.42 | 0.185-105.93 | 0.359 |
| mtDNA (ng/100 μL plasma) | > 174 | 320.54 | 14.42-7123.33 | 0.000 |
| Plasma variables2 | ||||
| IL-6 (pg/mL) | > 473.2 | 2.27 | 0.19-26.92 | 0.515 |
| IL-8 (pg/mL) | > 66.30 | 10.42 | 1.54-70.45 | 0.016 |
| IL-10 (pg/mL) | > 95.71 | 8.01 | 1.26-50.97 | 0.027 |
| TNFα (pg/mL) | > 313.7 | 0.27 | 0.03-2.17 | 0.220 |
| mtDNA (ng/100 μL plasma) | > 405.3 | 12.11 | 2.57-57.07 | 0.002 |
| INR | > 2.12 | 29.88 | 5.44-164.19 | 0.000 |
1
Multivariate analysis from clinical and inflammatory parameters associated with ALF;
2
Multivariate analysis from clinical and inflammatory parameters associated with death. OR: Odds ratio; IL: Interleukin; IFNγ: Interferon gamma; TNFα: Tumor necrosis factor alpha; mtDNA: Total mitochondrial DNA; ALF: Acute liver failure; INR: International normalized ratio.