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. 2016 Nov 14;7:13334. doi: 10.1038/ncomms13334

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Copyright © 2016, The Author(s)

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CENP-A is represented in red, histone H3 is represented in yellow and histone H4 in orange. See text for details. (a) Model for centrochromatin maintenance in a normal (wild type) situation. (b–d) Model of the effects observed after engineering the alphoid^tetO HAC centromere. HT, heterochromatin; TF, transcription factors.