Table 3. Baseline characteristics of patients with T2DM with various KCNQ1 rs2237892 (C/T) genotypes before the administration of repaglinide (n = 305).
| Parameter | CC (n = 148) | CT/TT (n = 157) | P value |
|---|---|---|---|
| Sex | |||
| Male | 90 | 95 | |
| Female | 58 | 62 | 0.957b |
| Age (years) | 49.10 ± 10.68 | 48.78 ± 12.93 | 0.812 |
| BMI (kg/m2) | 25.71 ± 3.22 | 26.47 ± 3.79 | 0.109c |
| WHR | 0.91 ± 0.07 | 0.91 ± 0.06 | 0.901c |
| FPG (mM) | 9.95 ± 2.62 | 9.88 ± 2.78 | 0.614c |
| PPG (mM) | 16.52 ± 4.47 | 16.20 ± 4.81 | 0.162c |
| FINS (mU/l) | 9.99 ± 6.90 | 13.93 ± 13.82 | 0.014* |
| PINS (mU/l) | 37.81 ± 46.19 | 57.37 ± 66.45 | 0.002**c |
| HOMA-IR | 4.24 ± 2.71 | 5.67 ± 4.92 | 0.046*c |
| HbA1c (%) | 9.42 ± 1.85 | 9.16 ± 2.28 | 0.02*c |
| TG (mM) | 2.49 ± 3.19 | 2.64 ± 2.66 | 0.182c |
| TC (mmol/l) | 5.25 ± 1.33 | 5.29 ± 1.27 | 0.629c |
| HDL-c (mM) | 1.43 ± 0.52 | 1.36 ± 0.45 | 0.128c |
| LDL-c (mM) | 3.19 ± 1.12 | 3.21 ± 1.04 | 0.971c |
Data are given as the mean ± SD.
bP values were determined using Pearson’s χ2 test.
cP values were determined using the Mann-Whitney test; all other P values were assessed using independent-samples t-tests. *P < 0.05,**P < 0.01.