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. 2016 Nov 14;7:13470. doi: 10.1038/ncomms13470

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Copyright © 2016, The Author(s)

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(a) Average normalized response to slow depolarizing voltage ramp (−100 to +10 mV; 59 mV s⁻¹) from SCN cells from WT during the mid-day (grey) or early-night (black). (b,c) Average normalized responses to voltage ramp from WT (black) or GSK3-KI (red) SCN cells during the day (b) or night (c). Scale bar, 5 pA, 5 mV. (d) Means±s.e.m. of peak inward current from cells in (a–c). Two-way ANOVA; main effect of time, F_(1,80)=7.009, P=0.01; main effect of genotype, F_(1,80)=7.506, P=0.008. For all panels: WT day, n=28 cells, five animals; WT night, n=22 cells, three animals; GSK3-KI day, n=18 cells, four animals; GSK3-KI night, n=16 cells, 3 animals.