Fig. 2.

Subnetworks that were significantly different between CAS and controls overlaid on a single image, shown on axial, coronal and sagittal planes (sagittal plane shows view from the left). Thin black lines represent edges (connections) whose average FA value does not correlate with any clinical measure. Brown edges represents: a) the connection between the opercular part of the left inferior frontal gyrus and the left middle temporal gyrus (subnetwork 1), whose average FA value correlates with low diadochokinesis rate (p = 0.01, R = 0.57), poor expressive grammar (p = 0.02, R = 0.53) and poor lexical production (p = 0.003, R = 0.67); b) the connection between the medial part of superior frontal gyrus and middle temporal gyrus (subnetwork 1), whose average FA value correlates with oromotor skills (p = 0.02, R = 0.56); c) the connection between the right superior occipital gyrus and left precuneus (subnetwork 2) whose average FA value correlates with low diadochokinesis rate (p = 0.01, R = 0.57).