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. 2016 Oct 24;12:910–927. doi: 10.1016/j.nicl.2016.10.015

Table 3.

Peak differences in FC between patients with lesions in the left temporal lobe and patients with lesions in the left frontal lobe.

Seeding from the LIFG
Region Peak t-value Correlation to lesion volume r-value (p-value) x, y, z-coordinate (MNI)
Patients with lesions in left temporal lobe > patients with lesions in the left frontal lobe
L Postcentral gyrus 5.17 − 0.09 − 38, − 34, 58
L Superior temporal gyrus 5.18 − 0.02 − 70, − 18, 2
R Inferior frontal gyrus, pars opercularis 5.07 0.05 34, 24, 16
R Frontal orbital cortex 4.05 0.2 42, 28, − 10
R Precentral gyrus 4.03 0.29 50, 6, 32
L Precentral gyrus 3.9 0.42 − 48, 0, 30
L Cingulate gyrus, anterior division 3.75 0.26 − 4, 14, 26
L Temporal pole 4.28 − 0.46 − 60, 10, − 6
L Frontal pole 3.3 − 0.14 − 48, 54, 0
R Postcentral gyrus 3.57 0.31 46, − 16, 46
L Supplementary motor area 3.76 0.35 − 6, − 6, 50
L Inferior frontal gyrus, pars triangularis 3.88 − 0.25 − 38, 24, 12
R Paracingulate gyrus 3.56 − 0.7 (p < 0.02) 6, 30, 36
R Insular cortex 4.43 0.76 (p < 0.007) 42, − 2, − 2
R Temporal occipital fusiform cortex 4.08 0.11 22, − 32, − 26
R Frontal pole 3.45 − 0.32 42, 54, 0
L Middle frontal gyrus 3.61 − 0.13 − 34, 28, 28
R Frontal pole 3.13 − 0.17 24, 40, 24
R Supramarginal gyrus 3.5 0.12 46, − 38, 40
R Superior frontal gyrus 3.54 0.56 36, − 30, 32
R Middle frontal gyrus 3.48 − 0.21 18, 16, 52
R Frontal pole 3.08 − 0.14 16



Patients with lesions in left frontal lobe > patients with lesions in the left temporal lobe
R Inferior temporal gyrus 4.52 0.03 42, − 12, − 40
R Occipital pole 4.13 − 0.37 12, − 96, 8
L Lingual gyrus 4.21 − 0.71 (p < 0.04) − 6, − 80, − 8
L Temporal occipital fusiform cortex 4.22 0.1 − 26, − 52, − 12
R Precuneous cortex 4.67 − 0.44 30, − 50, 10
R Temporal pole 3.58 0.22 46, 10, − 42
L Temporal pole 3.76 0.01 − 34, 20, − 42
L Cingulate gyrus, posterior division 4.09 0.46 − 16, − 46, 8
R Lateral occipital cortex, inferior division 5.04 − 0.28 30, − 72, 6
R Middle frontal gyrus 3.65 − 0.25 30, 0, 68
L Middle temporal gyrus, posterior division 4.48 − 0.22 − 62, − 6, − 36
R Cuneal cortex 3.42 − 0.29 0, − 78, 30
R Middle frontal gyrus 3.65 − 0.25 30, 0, 68
L Middle temporal gyrus, posterior division 4.48 − 0.22 − 62, − 6, − 36
R Cuneal cortex 3.42 − 0.29 0, − 78, 30
L Frontal pole 3.3 0.16 − 30, 48, 38
L Superior frontal gyrus 3.2 0.48 − 10, 30, 62
R Temporal occipital fusiform cortex 3.47 − 0.05 40, − 48, − 2
R Lingual gyrus 3.59 − 0.22 32, − 38, − 4
L Occipital fusiform gyrus 3.28 − 0.46 − 20, − 72, − 6
R Occipital fusiform gyrus 3.18 0.2 32, − 64, − 14
L Lateral occipital cortex, superior division 3.15 0.01 − 54, − 68, 40
L Precuneous cortex 3.23 0.03 − 16, − 50, 22



Seeding from the RIFG
Region Peak t-value Correlation to lesion volume r-value (p-value) x, y, z-coordinate (MNI)
Patients with lesions in left temporal lobe > patients with lesions in the left frontal lobe
R Inferior frontal gyrus, pars triangularis 5.09 − 0.35 30, 34, 12
L Precentral gyrus 5.78 − 0.01 − 64, 12, 20
R Precentral gyrus 4.4 0.38 46, − 2, 34
R Superior frontal gyrus 4.06 − 0.18 20, 38, 42
L Frontal pole 3.92 0.27 − 50, 46, − 8
L Precentral gyrus 4.12 − 0.18 − 34, − 14, 74
L Postcentral gyrus 3.59 − 0.27 − 46, − 22, 54
R Angular gyrus 3.79 − 0.71 (p < 0.02) 66, − 54, 36
L Planum polare 3.46 − 0.12 46, 2, − 6
R Inferior frontal gyrus, pars triangularis 3.6 − 0.73 ( < 0.02) 50, 28, 10
L Precentral gyrus 3.23 0.01 − 44, − 8, 34
R Frontal orbital cortex 3.36 0.35 40, 32, − 2
L Inferior frontal gyrus, pars opercularis 3.52 0.26 52, 18, 10
L Postcentral gyrus 3.03 − 0.48 − 40, − 34, 62



Patients with lesions in left frontal lobe > patients with lesions in the left temporal lobe
R Inferior temporal gyrus 3.56 0.41 46, − 18, − 36
R Superior parietal lobule 3.56 0.21 28, − 38, 44
L Temporal pole 3.91 − 0.37 − 38, 4, − 42
R Supramarginal gyrus 4.06 0.38 64, − 22, 24
L Lingual gyrus 4.08 0.26 − 4, − 80, − 10
R Occipital fusiform gyrus 4.43 0.19 20, − 74, − 20
L Temporal pole 3.76 − 0.6 − 46, 12, − 30
R Precuneous cortex 3.54 − 0.22 8, − 56, 60
L Parahippocampal gyrus, anterior division 3.71 − 0.57 − 24, 6, − 40
L Precuneous cortex 3.66 − 0.59 − 14, − 58, 44
R Lateral occipital cortex 3.17 − 0.06 50, − 66, − 16



Seeding from the LSTG
Region Peak t-value Correlation to lesion volume r-value (p-value) x, y, z-coordinate (MNI)
Patients with lesions in left temporal lobe > patients with lesions in the left frontal lobe
R Postcentral gyrus 5.42 − 0.19 64, − 10, 32
L Postcentral gyrus 3.94 − 0.38 − 54, − 12, 24
R Superior temporal gyrus 4.33 0.01 58, − 30, 10
L Precentral gyrus 3.83 − 0.12 − 62, − 2, 18
R Supramarginal gyrus 4.05 0.24 40, − 38, 24
R Frontal pole 3.71 0.09 42, 40, 44
L Superior parietal lobule 3.7 − 0.51 − 36, − 40, 58
L Superior temporal gyrus 3.8 0.05 − 70, − 16, 0
R Frontal pole 3.76 0.05 10, 68, 32
L Central opercular cortex 3.33 − 0.16 − 42, − 12, 10
L Cingulate gyrus, anterior division 3.44 0.13 − 8, 14, 22
L Lateral occipital cortex 3.25 0.48 − 24, − 68, 54
R Central opercular cortex 3.14 − 0.34 62, − 4, 10



Patients with lesions in left frontal lobe > patients with lesions in the left temporal lobe
L Frontal pole 6.3 0.03 − 22, 62, − 14
L Superior frontal gyrus 4.11 − 0.16 − 12, 10, 62
R Inferior temporal gyrus 3.65 − 0.53 − 64, − 30, 26
R Frontal orbital cortex 3.79 0.57 16, 6, − 12
L Precuneous cortex 3.9 0.24 − 16, − 54, 26
R Middle frontal gyrus 3.42 − 0.01 46, 22, 42
R Parahippocampal gyrus, anterior division 5.05 − 0.8 18, − 16, − 36
L Inferior temporal gyrus 3.55 0.24 − 44, − 16, − 46
R Lateral occipital cortex 3.67 − 0.73 (p < 0.03) 44, − 84, 10
R Frontal pole 3.34 − 0.29 22, 70, − 4
L Parahippocampal gyrus, anterior division 3.4 − 0.4 − 8, − 4, − 24
L Cingulate gyrus, posterior division 3.13 − 0.3 − 4, − 36, 46
L Lingual gyrus 3.34 − 0.15 − 8, − 80, − 16



Seeding from the RSTG
Region Peak t-value Correlation to lesion volume r-value (p-value) x, y, z-coordinate (MNI)
Patients with lesions in left temporal lobe > patients with lesions in the left frontal lobe
R Angular gyrus 8.3 0.12 64, − 46, 12
L Postcentral gyrus 5.82 0.01 − 22, − 18, 80
R Cingulate gyrus, posterior division 4.81 0.19 6, − 50, 16
R Lateral occipital cortex 5.62 0.24 54, − 72, 2
R Precentral gyrus 4.43 0.08 8, − 28, 80
L Lingual gyrus 4.26 − 0.13 − 16, − 56, − 10
R Frontal pole 4.64 0.18 22, 46, 50
L Lateral occipital cortex 3.92 − 0.06 − 46, − 72, 2
R Postcentral gyrus 3.67 0.19 50, − 16, 54
L Intracalcarine cortex 3.63 0.09 − 22, − 68, 12
L Central opercular cortex 3.63 0.64 (p < 0.04) − 50, − 12, 18
R Cuneal cortex 2.99 − 0.07 14, − 82, 26



Patients with lesions in left frontal lobe > patients with lesions in the left temporal lobe
R Frontal operculum cortex 5.16 − 0.2 48, 22, − 4
L Superior frontal gyrus 6.57 − 0.57 − 8, 24, 52
L Precentral gyrus 7.58 0.26 − 46, 0, 36
R Supramarginal gyrus 5.57 − 0.19 32, − 40, 36
L Frontal orbital cortex 4.95 − 0.29 − 36, 20, − 8
L Supramarginal gyrus 4.32 0.14 − 48, − 38, 44
R Frontal pole 3.85 0.13 38, 42, − 12
L Occipital fusiform gyrus 4.1 − 0.39 − 16, − 78, − 20
L Angular gyrus 3.56 − 0.05 − 44, − 54, 50
L Precentral gyrus 3.97 − 0.19 − 54, 6, 4
R Temporal fusiform cortex 3.35 − 0.2 22, − 2, − 44
L Supplementary motor cortex 3.26 − 0.4 − 6, − 8, 62
R Parahippocampal gyrus, anterior division 4.33 − 0.41 20, − 16, − 38
L Temporal pole 3.3 − 0.09 − 28, 8, − 48
L Precuneous cortex 3.24 − 0.27 − 10, − 74, 40
L Precentral gyrus 3.34 − 0.74 (p < 0.03) − 28, − 4, 44
R Cingulate gyrus, anterior division 3.15 0.08 6, 40, 10