Table 1.
Characteristic | No Recurrence N=226 | Recurrence N=133 | P-value |
---|---|---|---|
Age at diagnosis | |||
<55 | 36 (15.9) | 10 (7.5) | |
56–65 | 53 (23.5) | 47 (35.3) | |
66–75 | 71 (31.4) | 48 (36.1) | |
>75 | 66 (29.2) | 28 (21.1) | 0.05 |
Country | |||
United States | 159 (70.4) | 100 (75.2) | |
Other | 67 (29.7) | 33 (24.8) | 0.52 |
Race | |||
White | 176 (77.9) | 107 (80.5) | |
Black | 10 (4.4) | 10 (7.5) | |
Asian | 34 (15.0) | 9 (6.8) | |
Missing | 6 (2.7) | 7 (5.3) | 0.51 |
Gender | |||
Male | 172 (76.1) | 97 (72.9) | |
Female | 54 (23.9) | 36 (27.1) | 0.65 |
Smoking | |||
Never | 63 (27.9) | 33 (24.8) | |
Former (<30 pack-years) | 40 (17.7) | 22 (16.5) | |
Former (≥30 pack-years) | 34 (15.0) | 40 (30.1) | |
Current (<40 pack-years) | 22 (9.7) | 9 (6.8) | |
Current (≥40 pack-years) | 15 (6.6) | 14 (10.5) | |
Missing | 52 (23.0) | 15 (11.3) | 0.02 |
Pathologic stage (AJCC) | |||
Stage II | 93 (41.2) | 31 (23.3) | |
Stage III | 79 (35.0) | 39 (29.3) | |
Stage IV | 54 (23.9) | 63 (47.4) | <.0001 |
Histologic subtype | |||
Non-papillary | 141 (62.4) | 101 (75.9) | |
Papillary | 85 (37.6) | 32 (24.1) | 0.07 |
History of NMI | |||
No | 156 (69.0) | 74 (55.6) | |
Yes | 34 (15.0) | 28 (21.1) | |
Missing | 36 (15.9) | 31 (23.3) | 0.52 |
History of other malignancy | |||
No | 174 (77.0) | 89 (66.9) | |
Yes | 52 (23.0) | 44 (33.1) | 0.35 |
High-risk occupation | |||
No | 104 (46.0) | 55 (41.4) | |
Yes | 33 (14.6) | 36 (27.1) | |
Missing | 89 (39.4) | 42 (31.6) | 0.01 |
Abbreviations: American Joint Committee on Cancer (AJCC); Non-muscle invasive (NMI). P-values calculated using log-rank tests.