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. 2016 Nov 18;6:36862. doi: 10.1038/srep36862

Figure 1. Increased expression of pro-apoptotic receptor Fas (CD95) on CD27+ B-cells in cirrhosis.

Figure 1

(A) Representative FACS analyses and quantification of CD27 expression on CD19+ B-cells in healthy donors (HD) and cirrhotic patients (CIR). X marker indicates non-viral cirrhosis. Representative histograms and quantification of TRAIL-R1 (B), TRAIL-R2 (C) and CD95 (D) expression on CD27+ B-cells and CD27 B-cells in HD and CIR. Gray histogram is isotype control. Box plots represent median and interquartile range. Circles represent CD27 and boxes CD27+ B-cells. (E) Spearman correlation of CD27+ B-cell frequency and CD95 expression ex vivo.