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. 2016 Nov 18;6:36777. doi: 10.1038/srep36777

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Copyright © 2016, The Author(s)

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Chemical structures of the native substrates and products of each enzyme in the MEP pathway are depicted: 1-deoxy-_D-xylulose-5-phosphate synthase (DOXP Synthase); 1-deoxy-_D-xylulose-5-phosphate reductoisomerase (IspC); 2-C-methyl-_D-erythritol-4-phosphate cytidyltransferase (IspD); 4-diphosphocytidyl-2C-methyl-_D-erythritol kinase (IspE); 2-C-methyl-_D-eryth-ritol-2,4-cyclodiphosphate synthase (IspF); 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate synthase (IspG); 4-hydroxy-3-methyl-2-(E)-butenyl-4-diphosphate reductase (IspH).