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. 2016 Nov 18;3(6):ENEURO.0284-16.2016. doi: 10.1523/ENEURO.0284-16.2016

Figure 5.

Figure 5.

Tetrode recordings of single cell activity. A, Eight independent tetrodes were advanced into the dorsal hippocampus to target CA1 cells at the stratum pyramidale of normal and epileptic rats. Sections immunostained against NeuN were used to identify proximal and distal recording locations. Immunostaining against the CA2-specific protein PCP4 was used to validate proximal CA1 locations. Blue is bisbenzimide used to stain cell nuclei. B, Typical spike waveform and autocorrelogram of a putative pyramidal cell (red) and an interneuron (blue) recorded from an epileptic rat (KWGAT6). C, Units were classified according to several criteria, including spike width data. A group of units remained unclassified (gray). The number of units is given in the figure. Data from three control and three epileptic rats. D, Firing rate data from putative pyramidal cells and interneurons recorded at proximal and distal locations in control and epileptic rats. *p < 0.05; **p < 0.001.