Table 5.
Differentially expressed precursor miRNAs including Gms assigned as miRNA by Gencode with highest FC in kidney samples of the Ins2 Akita mice
| A | B | |||
|---|---|---|---|---|
| Gene | Fold change | Gene | DvC | TvD |
| Mir1247 | −86.22 | Gm24083 | 43.15 | −45.45 |
| Gm24083 | 43.15 | Gm25953 | 34.53 | −36.37 |
| Mir142b | −42.04 | Mir1905 | 29.52 | −5.19 |
| Gm25953 | 34.53 | Gm25535 | −28.56 | 23.41 |
| Mir1905 | 29.52 | Gm27903 | −26.25 | 11.75 |
| Gm25535 | −28.56 | Mir196a‐1 | 22.61 | −2.35 |
| Gm27903 | −26.25 | Gm25738 | −17.06 | 10.57 |
| Gm23251 | 22.85 | Gm25872 | −16.27 | 23.35 |
| Mir196a‐1 | 22.61 | Gm28010 | 15.43 | −3.08 |
| Mir27a | 20.80 | Mir6991 | 14.82 | −2.65 |
| Mirlet7b | 18.64 | Mir6364 | −12.80 | 8.06 |
| Gm25738 | −17.06 | Gm27684 | 12.51 | −1.86 |
| Mir6386 | 16.74 | Mir328 | −11.78 | 8.56 |
| Gm25872 | −16.27 | Mir1898 | −9.23 | 9.49 |
| Gm28010 | 15.43 | Gm25361 | −8.57 | 10.18 |
| Mir6991 | 14.82 | Gm23134 | −6.45 | 1.80 |
| Mir6981 | 13.64 | Mir7036 | −5.33 | 16.87 |
| Mir6364 | −12.80 | Mir7001 | −4.92 | 4.78 |
| Gm27684 | 12.51 | Mir3098 | 4.61 | −3.51 |
| Gm24515 | 11.93 | Gm27768 | −3.70 | 4.45 |
| Mir328 | −11.78 | Gm25233 | −3.70 | 4.45 |
| Gm25297 | 11.09 | Gm22734 | −3.70 | 4.45 |
| Mir1898 | −9.23 | Gm26043 | 2.96 | −8.34 |
| Gm25361 | −8.57 | Gm22721 | −2.76 | 2.17 |
| Gm27920 | 7.86 | Gm25640 | −2.43 | 6.59 |
| Gm27512 | 7.53 | Mir6363 | −2.08 | 2.27 |
| Gm28033 | 7.13 | Gm25190 | −1.93 | 2.33 |
| Gm23134 | −6.45 | Mir27b | −1.84 | 2.01 |
| Gm23268 | −5.97 | Mir3082 | −1.66 | 1.57 |
A. miRNAs regulated by diabetes with FC > =(+/-)5.97 (q < 0.05) relative to control.Genes are listed by highest numerical FC values (positive or negative), B. miRNAs with expression levels altered by diabetes that were reversed by P78 treatment. Genes are listed by highest numerical FC values (FC > =+/-1.66, q < 0.05) in DvC (first column) and the relative regulation values of these same genes after treatment (TvD) given in the second column