Table 3.
Comparison of diagnostic accuracy between US-guided biopsy and standard biopsy
| CNB (n = 156) | SPB (n = 160) | CNB + SPB (n = 166) | Statistical significance | |
|---|---|---|---|---|
| FN | 40 | 30 | 10 | NA |
| TN | 74 | 78 | 78 | NA |
| TP | 42 | 52 | 78 | NA |
| FP | 0 | 0 | 0 | NA |
| Sensitivity | 51.2% | 63.4% | 88.6% | p = 0.147, 0.000, 0.000* |
| Specificity | 100% | 100% | 100% | NA |
| PPV | 100% | 100% | 100% | NA |
| NPV | 64.9% | 72.2% | 88.6% | p = 0.394, 0.000, 0.009* |
| Diagnostic accuracy | 74.4% | 81.3% | 93.9% | p = 0.341, 0.001, 0.017* |
CNB cutting-needle biopsy, FN false-negative, FP false-positive, NA not applicable, NPV negative-predictive value, PPV positive-predictive value, SPB standard pleural biopsy, TN true-negative, TP true-positive, US ultrasound
*p-values for CNB vs SPB; CNB + SPB vs CNB; and CNB + SPB vs SPB