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. 2016 Nov 17;4:60. doi: 10.1186/s40168-016-0206-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Relative abundance at the family, genus, and OTU levels. RA BAL samples showed a significant decrease in Actynomyces (and related OTUs), Burkholderia (and related OTUs), and Treponema (and Prevotella-related OTU), compared to healthy controls. A similar trend for Burkholderia and the family Spirochaetaceae was observed for sarcoid BAL. The relative abundance (and presence) of the genus Porphyromonas in healthy BAL was also higher than in RA and sarcoid samples. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001; ns non-significant