Table 6.

Multivariable analysis in validation cohort

	OS		PFS
	HR (95% CI)	p	HR (95% CI)	p
UBE2E1 expression, high vs. low	3.227(1.05,9.852)	0.040	3.818(1.616,12.553)	0.027
Age, per 10-year increase	1.666(1.112,2.498)	0.013	1.536(1.02,2.313)	0.040
Sex, male vs. female	0.628(0.214,1.84)	0.396	0.559(0.183,1.71)	0.308
Performance status	0.727(0.374,1.41)	0.345	0.683(0.344,1.358)	0.277
Induction chemo-response	1.472(0.845,2.566)	0.172	1.51(0.853,2.672)	0.157