Table 2.
Up-regulated and down-regulated genes in centromere-46.75 Mb (R2 and R3 regions) of chromosome 12 in the epididymal fat in the A/J-12SM consomic strain
| Symbol | Gene name | Position (Mbp) | Region | Fold changea | Gene bank ID |
|---|---|---|---|---|---|
| Pfn4 | profilin family, member 4 | 4.76 | R2 | 0.525 | NM_028376 |
| Fkbp1b | FK506 binding protein 1b | 4.83 | R2 | 0.557 | NM_016863 |
| Apob | apolipoprotein B | 7.97 | R2 | 7.460 | NM_009693 |
| Nt5c1b | 5’-nucleotidase, cytosolic IB | 10.36 | R2 | 0.296 | NM_027588 |
| Ntsr2 | neurotensin receptor 2 | 16.65 | R2 | 1.896 | NM_008747 |
| Zfp125 | zinc finger protein 125 | 20.89 | R2 | 0.104 | AJ005350 |
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 26.44 | R2 | 0.580 | NM_021384 |
| Cmpk2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 26.46 | R2 | 0.463 | NM_020557 |
| Allc | allantoicase | 28.55 | R2 | 0.366 | NM_053156 |
| Sh3yl1 | Sh3 domain YSC-like 1 | 30.91 | R3 | 0.565 | NM_013709 |
| Slc26a3 | solute carrier family 26, member 3 | 31.39 | R3 | 0.361 | ENSMUST 00000001254 |
| Gdap10 | ganglioside-induced differentiation-associated-protein 10 | 32.82 | R3 | 1.928 | BC052902 |
| Cdhr3 | cadherin-related family member 3 | 33.03 | R3 | 0.557 | NM_001024478 |
| Efcab10 | EF-hand calcium binding domain 10 | 33.39 | R3 | 0.578 | NM_029152 |
| Mir680-3 | microRNA 680-3 | 35.19 | R3 | 2.545 | NR_030449 |
| Dgkb | diacylglycerol kinase, beta | 37.88 | R3 | 1.879 | NM_178681 |
| Nrcam | neuronal cell adhesion molecule | 44.32 | R3 | 0.529 | NM_176930 |
| Stxbp6 | syntaxin binding protein 6 (amisyn) | 44.85 | R3 | 3.307 | NM_144552 |
| Nova1 | neuro-oncological ventral antigen 1 | 46.69 | R3 | 1.908 | NM_021361 |
Up-regulated (log20.75, >1.68-fold) and down-regulated (log2-0.75, <0.60-fold) genes were identified from a DNA microarray analysis between A/J and A/J-12SM mice
aFold change was calculated by the gene expression level in A/J-12SM relative to that in A/J mice