Table 1.
Calculated sensitivities and specificities of various serum or plasma basal cortisol concentrations for the diagnosis of hypoadrenocorticism in dogs
| Basal Cortisol (nmol/L) | Dogs with HA (total n = 163) | Dogs with NAI (total n = 351) | % Sensitivity (95% CI) | % Specificity (95% CI) |
|---|---|---|---|---|
| ≤5.5 | 133 | 3 | 81.6 (74.8–87.2) | 99.1 (97.5–99.8) |
| ≤10 | 144 | 4 | 88.3 (82.4–92.8) | 98.9 (97.1–99.7) |
| ≤22 | 158 | 15 | 96.9 (93.0–99.0) | 95.7 (93.0–97.6) |
| ≤28 | 160 | 30 | 98.2 (94.7–99.6) | 91.5 (88.0–94.2) |
| ≤40 | 162 | 61 | 99.4 (96.6–100) | 82.6 (78.2–86.4) |
| ≤55 | 162 | 116 | 99.4 (96.6–100) | 67.0 (61.8–71.8) |
The number of dogs with hypoadrenocorticism and nonadrenal illness with basal cortisol concentrations ≤ the listed cut‐point are presented in the first 2 columns. The calculated sensitivity and specificity (and their respective 95% confidence intervals) are presented in the latter 2 columns. HA, hypoadrenocorticism; NAI, nonadrenal illness; CI, confidence interval.