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. 2016 Sep 28;30(6):1765–1779. doi: 10.1111/jvim.14586

Table 6.

Numbers of dogs for which administration of medication represented the first event in the “time to first event” including the type of medication administered and the reasons given for initiating medication. Note that more than 1 reason could be given for administration of medication and therefore the numbers in the “reason for administration” may not add up to the total in the adjacent column

Indication Type of medication introduced Pimobendan Placebo Total
Number (% of those at risk) Reason for administration Number (% of those at risk) Reason for administration Number (% of those at risk)
Cardiac indication Table 1 medication 8/178 (4.5%) Suspected but not verified CHF = 3
Weakness, collapse anorexia = 3
Persistent tachypnoea = 1
Systolic arterial hypotension = 1
Pulmonary hypertension = 2
Coughing = 2
Poor body condition = 1
Syncope = 2
Inappetence = 1
13/176 (7.4%) Suspected but not verified CHF = 5
Persistent tachypnoea = 1
Arrhythmia = 2
Coughing = 2
Syncope = 1
Right‐sided heart failure = 1
Persistent sinus tachycardia = 1
21/354 (5.9%)
Table 2 medication 1/178 (0.6%) Coughing 3/176 (1.7%) Coughing = 3
Weakness, collapse, anorexia = 1
4/354 (1.1%)
Noncardiac indication Table 1 medication 3/178 (1.7%) Dental procedure = 2
Neurological disease = 1
3/176 (1.7%) Sedation/anesthesia = 2
Proteinuria = 1
6/354 (1.7%)
Table 2 medication 34/178 (19.1%) Coughing = 19
Dermatologic disease = 7
Immune‐mediated disease = 4
Neurologic disease = 2
Endocrinopathy = 1
Unknown = 1
32/176 (18.2%) Coughing = 19
Neurologic disease = 3
Dermatologic disease = 3
Endocrinopathy = 1
Respiratory disease = 3
Immune‐mediated disease = 1
Behavioral problem = 1
Hypertension = 1
66/354 (18.6%)
Total 46/178 (25.8%) 51/176 (29.0%) 97/354 (27.4%)