Tryptophan metabolism in embryo rat brains. The charts summarise the concentrations of (A) tryptophan, (B) kynurenine, (C) kynurenic acid, (D) 3-hydroxykynurenine, (E) xanthurenic acid, (F) anthranilic acid and (G) quinolinic acid in the brains of rat embryos 5 h after the intraperitoneal administration of Ro61-8048 to the mother. ***P < 0.001 (paired t-test, n = 6).