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. 2016 Nov 18;11(11):e0166183. doi: 10.1371/journal.pone.0166183

Table 1. Clinical and pathological parameters.

Variable No upstaging (N = 896) Upstaging (N = 91) P-value
Age (years), mean ± SD 54.9 ± 12.6 58.6 ± 13.9 0.006
Sex, no. (%) 0.712
Men 647 (72.2) 68 (74.7)
Women 249 (27.8) 23 (25.3)
BMI (kg/m2), mean ± SD 24.6 ± 3.2 24.7 ± 3.1 0.651
Clinical stage < 0.001
T1a 798 (89.1) 48 (52.7)
T1b 98 (10.9) 43 (47.3)
Symptoms (%) 97 (10.8) 21 (21.8) 0.002
Follow-up (months), mean ± SD 48.2 ± 27.2 50.8 ± 32.4 0.752
Pathological T stage (%) N.A.
T1a 499 (89.2)
T1b 97 (10.8)
Histology (%) 0.134
Clear cell 721 (80.5) 69 (75.8)
Papillary 81 (9.0) 7 (7.7)
Chromophobe 69 (7.7) 11 (12.1)
Other 25 (2.8) 4 (4.4)
Fuhrman grade (%) < 0.001
1 88 (9.8) 1 (1.1)
2 553 (61.7) 32 (35.2)
3 242 (27.0) 50 (54.9)
4 11 (1.2) 8 (8.8)
Positive surgical margin, no. (%) 33 (3.7) 2 (2.2) 0.764
Pseudosarcomatous component, no. (%) 2 (0.2) 4 (4.4) 0.001

SD: standard deviation; BMI: body mass index.