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. 2016 Nov 18;11(11):e0166680. doi: 10.1371/journal.pone.0166680

Table 4. Univariate and multivariate analysis of factors for breast cancer-specific survival.

Variables Reference Univariate analysis Multivariate analysis
p value HR 95% CI p value HR 95% CI
Lower Upper Lower Upper
Menopause pre vs. post post 0.79 1.18 0.31 3.92
Tumor size ≦2cm vs. >2cm ≦2cm 0.11 3.14 0.8 20.7 0.081 15.1 0.74 438.9
Clinical stage 1 vs 2, 3 1 0.53 1.52 0.43 6.99 0.32 0.23 0.015 4.18
Nodal status positive vs. negative negative 0.32 1.84 0.55 6.4
Nuclear Grade 1 vs 2, 3 1 0.16 2.47 0.71 11.3
ERα negative vs. positive positive <0.001 14 3.61 92.2 0.0012 18.7 2.97 172.9
PgR negative vs. positive positive 0.013 4.78 1.37 21.9 0.95 0.94 0.16 6.57
Her2 positive vs. negative negative 0.78 1.22 0.26 4.24 0.22 0.38 0.069 1.77
Ki67 > 20% vs. ≦20% ≦20% 0.054 0.97 0.41 94 0.72 1.50 0.20 30.6
CD68 low vs. high low 0.73 0.81 0.23 2.71
CD169 low vs. high high 0.3 0.53 0.14 1.75 0.55 0.49 0.060 5.55
CD169/CD68 low vs. high high 0.74 0.82 0.24 2.72 0.75 0.68 0.048 6.07
CD8 low vs. high high 0.82 0.87 0.25 2.89 0.75 0.80 0.19 3.09