Table 4. Univariate and multivariate analysis of factors for breast cancer-specific survival.
Variables | Reference | Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|---|---|
p value | HR | 95% CI | p value | HR | 95% CI | |||||
Lower | Upper | Lower | Upper | |||||||
Menopause | pre vs. post | post | 0.79 | 1.18 | 0.31 | 3.92 | ||||
Tumor size | ≦2cm vs. >2cm | ≦2cm | 0.11 | 3.14 | 0.8 | 20.7 | 0.081 | 15.1 | 0.74 | 438.9 |
Clinical stage | 1 vs 2, 3 | 1 | 0.53 | 1.52 | 0.43 | 6.99 | 0.32 | 0.23 | 0.015 | 4.18 |
Nodal status | positive vs. negative | negative | 0.32 | 1.84 | 0.55 | 6.4 | ||||
Nuclear Grade | 1 vs 2, 3 | 1 | 0.16 | 2.47 | 0.71 | 11.3 | ||||
ERα | negative vs. positive | positive | <0.001 | 14 | 3.61 | 92.2 | 0.0012 | 18.7 | 2.97 | 172.9 |
PgR | negative vs. positive | positive | 0.013 | 4.78 | 1.37 | 21.9 | 0.95 | 0.94 | 0.16 | 6.57 |
Her2 | positive vs. negative | negative | 0.78 | 1.22 | 0.26 | 4.24 | 0.22 | 0.38 | 0.069 | 1.77 |
Ki67 | > 20% vs. ≦20% | ≦20% | 0.054 | 0.97 | 0.41 | 94 | 0.72 | 1.50 | 0.20 | 30.6 |
CD68 | low vs. high | low | 0.73 | 0.81 | 0.23 | 2.71 | ||||
CD169 | low vs. high | high | 0.3 | 0.53 | 0.14 | 1.75 | 0.55 | 0.49 | 0.060 | 5.55 |
CD169/CD68 | low vs. high | high | 0.74 | 0.82 | 0.24 | 2.72 | 0.75 | 0.68 | 0.048 | 6.07 |
CD8 | low vs. high | high | 0.82 | 0.87 | 0.25 | 2.89 | 0.75 | 0.80 | 0.19 | 3.09 |