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. 2016 Nov 18;11(11):e0166801. doi: 10.1371/journal.pone.0166801

Table 1. Characteristics of Included Studies Comparing Different treatments for displaced proximal humeral fracture.

Study Country Interventions Sample size (mean age: y) Follow-up (month) Study design For analysis
Dietrich 2008 Germany ORIF vs HA 52(82)/59(80) 12 RC Constant score; Total complications; Incidence of additional surgeries
Bastian 2009 Switzerland ORIF vs HA 44(60)/33(60) 60 PC Constant score; Total complications; Incidence of additional surgeries
Solberg 2009 USA ORIF vs HA 38(66.5)/48(67.4) 36 RC Constant score; Total complications; Incidence of additional surgeries
Wang 2009 China ORIF vs HA 12(49)/10(49) 20 RC Constant score; Total complications
Zhang 2010 China ORIF vs HA 28(66.5)/30(68.9) 28 RC Constant score; Total complications
Kim 2011 Korea ORIF vs HA 38(64.9)/26(64.9) 24 RC Constant score; Total complications; Incidence of additional surgeries
Wild 2011 USA ORIF vs HA 42(56.9)/15(66.4) 35 RC Constant score; Total complications; Incidence of additional surgeries
Spross 2011 Switzerland ORIF vs HA 22(75)/22(76) 30 RC Constant score; Total complications; Incidence of additional surgeries
Cai 2012 China ORIF vs HA 13(72)/19(72) 24 RCT Constant score
Lu 2012 China ORIF vs HA 26(67)/22(67) 6 RC Constant score; Total complications
Gallinet 2009 France HA vs RSA 17(74)/16(74) 14.5 RC Constant score; Total complications
Young 2010 New Zealand HA vs RSA 10(75.5)/10(77.2) 33 RC Total complications
Garrigues 2012 USA HA vs RSA 9(69.3)/10(80.5) 43.2 RC Total complications
Boyle 2013 New Zealand HA vs RSA 313(71.9)/55(79.6) 12 RC Incidence of additional surgeries
Cuff 2013 USA HA vs RSA 23(74.4)/24(74.4) 24 PC Total complications; Incidence of additional surgeries
Fu 2013 China HA vs RSA 12(69.5)/11(81.2) 43.2 RC Total complications
Baudi 2014 Italy HA vs RSA 28(71.4)/25(77.3) 27.5 RC Constant score; Total complications
Chalmers 2014 USA HA vs RSA 9(72)/9(77) 12 RC Total complications
Sebastia-Forcada 2014 Spain HA vs RSA 30(73.3)/31(74.7) 28.5 RCT Constant score; Total complications; Incidence of additional surgeries
Gradl 2009 Germany ORIF vs IN 76(63)/76(62) 12 PC Constant score; Total complications; Incidence of additional surgeries
Matziolis 2010 Germany ORIF vs IN 11(54.8)/11(55.6) 36 RC Constant score; Total complications; Incidence of additional surgeries
Smejkal 2011 Chech ORIF vs IN 28(61)/27(61) 2–18 RCT Constant score; Total complications
Trepat 2011 Spain ORIF vs IN 14(68.3)/15(64.5) 6–12 RC Total complications; Incidence of additional surgeries
Zhu 2011 China ORIF vs IN 26(50.5)/25(54.8) 12–36 RCT Constant score; Total complications; Incidence of additional surgeries
Lekic 2012 USA ORIF vs IN 12(59)/11(60) 3–46 RC Total complications; Incidence of additional surgeries
Konrad 2012 Switzerland ORIF vs IN 153(65.4)/58(64.8) 3–12 PC Constant score; Total complications; Incidence of additional surgeries
Von 2014 Germany ORIF vs IN 28(61)/44(61) 38–82 RC Total complications; Incidence of additional surgeries
Zyto 1997 Sweden ORIF vs NOT 20(73)/20(75) 36–60 RCT Constant score; Total complications
Olerud 2011a Sweden ORIF vs NOT 30(74)/30(74) 24 RCT Constant score; Total complications; Incidence of additional surgeries
Kollig 2003 Germany ORIF vs NOT 13(52.5)/ 9(52.7) 74–82 PC Constant score
Fjalestad 2014 Norway ORIF vs NOT 25(72.2)/25(73.1) 24 RCT Constant score; Total complications; Incidence of additional surgeries
Stableforth 1984 England HA vs NOT 16(65.6)/16(70.1) 6–48 RCT Total complications
Olerud 2011b Sweden HA vs NOT 27(75.8)/28(77.5) 24 RCT Constant score; Total complications; Incidence of additional surgeries
Boons 2012 Netherlands HA vs NOT 25(76.4)/25(79.9) 24 RCT Constant score; Total complications; Incidence of additional surgeries

ORIF: open reduction and internal fixation; HA: hemiarthroplasty; RSA: reverse shoulder arthroplasty; IN: intramedullary nailing; NOT: Non-operative treatment; RC: Retrospective comparative; PC: Prospective comparative; RCT: Randomised controlled trial; y: years.