Table 1. Patients characteristics.

Variables	Subjects (n = 17)
Age (years), median, IQR*	71, 66–80
Gender (Male / Female)	14 / 3
Body mass index (kg/m2), median, IQR*	22.0, 20.8–22.8
Comorbidities
Smoking history, number, percentage	12, 70.6%
Hypertension, number, percentage	14, 82.4%
Dyslipidemia, number, percentage	12, 70.6%
Coronary artery disease, number, percentage	3, 17.6%
Cerebrovascular disease, number, percentage	5, 29.4%
Diabetes mellitus, number, percentage	12, 70.6%
Medications
Ca-blocker, number, percentage	10, 58.8%
β-blocker, number, percentage	3, 17.6%
Hemodynamical parameters
Ankle brachial pressure index, median, IQR*	0.82, 0.63–0.98
Reactive hyperemia index, median, IQR*	1.46, 1.36–1.68
Laboratory findings
White blood cell (/μl), median, IQR*	6400, 5700–7300
Hemoglobin (g/dl), median, IQR*	12.8, 12.2–14.7
Platelet (x104/μl), median, IQR*	21.6, 18.9–25.2
Prothrombin time (%), median, IQR*	101.8, 91.7–107.3
Activated partial thromboplastin time (sec), median, IQR*	28.4, 27–30.1
Fibrinogen (mg/dl), median, IQR*	304, 269–317
D-Dimer (μg/ml), median, IQR*	1.06, 0.78–2.10
Creatinine (mg/dl), median, IQR*	0.92, 0.78–1.44
Total cholesterol (mg/dl), median, IQR*	193, 160–205
Triglycerides (mg/dl), median, IQR*	92, 71–205
High-density lipoprotein (mg/dl), median, IQR*	54, 48–67
Low-density lipoprotein (mg/dl), median, IQR*	116, 101–121
Hemoglobin A1c (%), median, IQR*	6.75, 6.45–7.05
C-reactive protein (mg/dl), median, IQR*	0.08, 0.05–0.17
Thrombomodulin (FU/ml)	18.5, 13.7–21.3

* IQR, interquartile range.