Table 1. MS 6q23 Immunochip associated regions.
Region Co-ordinates (GRCh37) | Index SNP | Reported Gene | MAF | P | OR | ||
---|---|---|---|---|---|---|---|
Chr. | Start | End | |||||
6 | 134946991 | 135498875 | rs11154801 | AHI1 | 0.37 | 1.80 x 10−20 | 1.12 |
6 | 136685539 | 136875216 | rs17066096 | IL22RA2 | 0.23 | 1.60 x 10−23 | 1.14 |
6 | 137231416 | 137660037 | rs7769192a | - | 0.45 | 3.30 x 10−09 | 1.08 |
rs67297943 | TNFAIP3 | 0.22 | 5.50 x 10−13 | 1.11 |
All P values are from the joint analysis by Beecham et al.[6]. Chr., chromosome; MAF, minor allele frequency; OR, odds ratio.
a, P values and ORs shown after conditioning on rs67297943.