Table 12. Identifying splicing factors that binds to combinatorial SREs in the brain tissue.
| Combinatorial SRE set | Enhancer factor | Inhibitor factor | Brain ratio | Heart ratio | Liver ratio | Muscle ratio |
|---|---|---|---|---|---|---|
| CAAGGA, CAGCCA | FMRP | hnRNPLL | 1.831381681 | 1.484036726 | 1.899282779 | 0.521982767 |
| TGTGGA, CCAGCA | SRp55 | hnRNPLL | 1.706009449 | 2.279634755 | 7.114715878 | 0.846707243 |
| TGTGGA, CAGCCA | SRp55 | hnRNPLL | 1.706009449 | 2.279634755 | 7.114715878 | 0.846707243 |
| TGTGGA, TCCTTT | SRp55 | DAZAP1 | 1.162119086 | 0.935388956 | 1.786036684 | 0.356244555 |
| GAAGGC, AGGCAG | 9G8 | non | - | - | - | - |
| AGAAGAT, TTAGAA | 9G8 | non | - | - | - | - |
| GAAGGA, GGGAGG | HTra2beta1 | hnRNP F | 0.113064576 | 0.131103394 | 0.053528796 | 0.09326604 |
| TTCTTC, TCCTTT | non | hnRNPA2B1 | - | - | - | - |
| GAGGAT, GGGAGG | SF2/ASF | hnRNPA1 | 0.064157386 | 0.086308919 | 0.183388318 | 0.052519222 |
| GAGGAT, GGGAGG | SF2/ASF | hnRNPF | 0.697677691 | 0.761178655 | 0.350434389 | 0.316325285 |
The ratio columns contain the ration between the expression level of the enhancer factor and the inhibitor factor in the specified tissue. The cells with ‘non’ indicates that we could not identify an associated splicing factor and hence no ratios are provided.