Table 4. Results of three common healthspan measures in four studies of aged C57BL/6 mice.

Measure	Assay	Comparison	Ages (months)	Aged Females	Aged Males	Citation
Grip strength	Force gauge	Cross-sectional	4, 20, 28, 32	Lower	Lower	This study
Grip strength	Wire hang	Cross-sectional	3, 8, 15, 30	Lower		[19]
Grip strength	Wire hang	Cross-sectional	4, 22, 28		Lower	[20]
Grip strength	Force gauge	Cross-sectional	3, 20, 26		Lower	[21]
Activity	12 hour, dark phase	Cross-sectional	4, 20, 28, 32	Lower	Lower	This study
Activity	90 min, light phase	Cross-sectional	3, 8, 15, 30	Little difference		[19]
Activity	60 min, light phase	Cross-sectional	4, 22, 28		Lower	[20]
Activity	5 min, light phase	Cross-sectional	3, 20, 26		Lower	[21]
Rotarod	Accelerating 4-40rpm, 300 sec	Cross-sectional	4, 20, 28, 32	No difference	Lower	This study
Rotarod	Accelerating 0-40rpm, 300 sec	Cross-sectional	4, 22, 28		Lower	[20]
Rotarod	Accelerating 4-40rpm, 300 sec	Cross-sectional	3, 20, 26		Lower	[21]