Table 2. Female characteristics according to IGF-I tertiles.
| Female Characteristics | IGF-I Tertile 1(n=55) | IGF-I Tertiles 2 and 3 (n=108) | p-value |
|---|---|---|---|
| Age, years | 97.3 (96.3-99.0) | 97.1(95.9-100.3) | 0.97 |
| Height, m (n=131) | 1.59±0.05 | 1.59±0.06 | 0.41 |
| BMI, kg/m2 (n=128) | 21.0±3.0 | 21.6±3.3 | 0.33 |
| IGF-I, ng/mL | 58±13(range 25-75) | 119±35(range 76-268) | <0.01 |
| IGFBP-1, ng/mL (n=155) | 17 (5-33) | 15.5 (0-26) | 0.15 |
| IGFBP-3, mg/mL, (n=161) | 2.6±0.7 | 3.7±0.9 | <0.01 |
| IGF-I/IGFBP-3 molar ratio, (n=161) | 0.09±0.03 | 0.12±0.03 | <0.01 |
| Glucose, mg/dL, (n=145) | 99±35 | 107±47 | 0.34 |
| 25(OH)2 vitamin D, mg/dL, (n=97) | 26.8±11.9 | 26.5±10.2 | 0.89 |
| MMSE score* (n=123) | 29 (8-30) | 27 (2-30) | 0.04 |
| Hypertension, % (n=153) | 54.7 | 60.0 | 0.53 |
| Cardiovascular disease, % (n=155) | 24.1 | 28.7 | 0.54 |
| Diabetes mellitus, % (n=155) | 9.3 | 8.9 | 0.94 |
| Cancer, % (n=153) | 28.9 | 15.8 | 0.06 |
| Education, years (n=133) | 13.6±3.4 | 12.9±3.1 | 0.22 |
| Depression (%), (n=115) | 35.0 | 44.0 | 0.35 |
| Tobacco use, ever (%), (n=144) | 46.9 | 25.3 | <0.01 |
| Alcohol use at age 70 yrs (%), (n=139) | 57.5 | 44.6 | 0.15 |
*
Median (IQR) scores for MMSE exclude subjects who were scored using the blind MMSE.