Table 3. Male characteristics according to IGF-I tertiles.
| Male Characteristics | IGF-I Tertile 1 (n=14) | IGF-I Tertiles 2 and 3 (n=26) | p-value |
|---|---|---|---|
| Age, years | 98 (96.2-99.4) | 97.2 (96.3-100) | 0.57 |
| Height, m (n=35) | 1.69±0.08 | 1.73±0.08 | 0.26 |
| BMI, kg/m2 (n=33) | 20.3±2.0 | 21.9±2.4 | 0.09 |
| IGF-I, ng/mL | 55±8 (range 36-65) | 104±26 (range 69-164) | <0.01 |
| IGFBP-1, ng/mL | 22 (10-54) | 14 (0-25) | 0.23 |
| IGFBP-3, mg/mL | 2.2 ±0.8 | 2.8±0.8 | 0.02 |
| IGF-I/IGFBP-3 molar ratio | 0.10±0.05 | 0.13±0.04 | 0.01 |
| Glucose, mg/dL, (n=38) | 98±24 | 101±30 | 0.81 |
| 25(OH)2 vitamin D, mg/dL, (n=18) | 20.7±9.2 | 29.5±11.1 | 0.17 |
| MMSE score* (n=34) | 27.5 (24-30) | 29 (25-30) | 0.24 |
| Hypertension, % (n=39) | 35.7 | 44.0 | 0.61 |
| Cardiovascular disease, % (n=37) | 46.2 | 37.5 | 0.61 |
| Diabetes mellitus, % (n=37) | 7.7 | 16.7 | 0.64 |
| Cancer, % (n=40) | 28.6 | 7.7 | 0.16 |
| Education, years (n=35) | 14.3±5.8 | 15.7±6.3 | 0.51 |
| Depression (%), (n=33) | 33.3 | 14.3 | 0.38 |
| Tobacco use, ever (%), (n=35) | 33.3 | 52.2 | 0.29 |
| Alcohol use at age 70 yrs (%), (n=35) | 91.7 | 78.3 | 0.64 |
*
Median (IQR) scores for MMSE exclude subjects who were scored using the blind MMSE.